Scientists produce personalised skin cancer vaccine

Two clinical trials for skin cancer have proven that vaccines tailor-made to target a particular patient’s tumours are safe.

The vaccines are detailed in papers published in the Nature journal this July.

Although it does not equate to a cure, the study could combat cancer in humans. They also provide hints about ways to boost the vaccines' power by combining them with treatments that target the immune system, called immunotherapies.

The study took six patients diagnosed with malignant melanoma who had undergone initial treatment.

Naked Scientist Chris Smith explains more.

What they then did was to sequence the DNA of the tumor and then the healthy tissue and compare the two.

Chris Smith, The Naked Scientist

They were looking for were the genetic differences between the tumor and the healthy tissue.

They then used a computer programme to ask of these differences, which ones would be reflected in a difference on the surfaces of cancer cells in terms of the chemical markers they display, and which ones would be most apparent to the immune system.

Chris Smith, The Naked Scientist

Once they got a short list, they made the proteins that those mutated genes would have made in the cancer cells and turned them into a vaccine.

Chris Smith, The Naked Scientist

He says none have had a relapse in two years.

Click on the link below to listen to the full audio....


Recommended

by THE NEWSROOM

702 welcomes all comments that are constructive, contribute to discussions in a meaningful manner and take stories forward.

However, we will NOT condone the following:

  • Racism (including offensive comments based on ethnicity and nationality)
  • Sexism
  • Homophobia
  • Religious intolerance
  • Cyber bullying
  • Hate speech
  • Derogatory language
  • Comments inciting violence.

We ask that your comments remain relevant to the articles they appear on and do not include general banter or conversation as this dilutes the effectiveness of the comments section.

We strive to make the 702 community a safe and welcoming space for all.

702 reserves the right to: 1) remove any comments that do not follow the above guidelines; and, 2) ban users who repeatedly infringe the rules.

Should you find any comments upsetting or offensive you can also flag them and we will assess it against our guidelines.

702 is constantly reviewing its comments policy in order to create an environment conducive to constructive conversations.

Read More
Journos join the dots: Estina suspects, 'Zupta empire' and state capture in SA

Journos join the dots: Estina suspects, 'Zupta empire' and state capture in SA

Senior investigative journos unravel the Estina Dairy Farm scandal and how the suspects fit into the bigger state capture project.

[LISTEN] Blade Nzimande says he is available to serve in Cabinet again

[LISTEN] Blade Nzimande says he is available to serve in Cabinet again

SACP leader Dr Blade Nzimande who was axed as Higher Education Minister by Jacob Zuma says he would serve under Cyril Ramaphosa.

[LISTEN] I'm cutting out the middleman -  Herman Mashaba

[LISTEN] I'm cutting out the middleman - Herman Mashaba

City of Johannesburg Mayor Herman Mashaba is adamant there's no conflict of interest in getting his friend to help in the city

Reward for Gupta arrest could jeopardise case, warns security expert

Reward for Gupta arrest could jeopardise case, warns security expert

Ajay Gupta and his associates are on the run, but rewards being offered for their arrest could do more harm than good.

5 signs that you're a victim of passive aggressive behaviour

5 signs that you're a victim of passive aggressive behaviour

No, you're not imagining things. Passive aggressive behaviour is usually difficult to recognise at first, a psychotherapist says.

Analysts Mnguni, Mde and Judith February reflect on Ramaphosa's Sona

Analysts Mnguni, Mde and Judith February reflect on Ramaphosa's Sona

Political analysts unpack the 2018 State Of the Nation Address with Eusebius McKaiser.

Popular articles
"Duduzane Zuma is the Gupta family's greatest asset"

"Duduzane Zuma is the Gupta family's greatest asset"

Sunday Times journo Thanduxolo Jika who broke the front page story about the Gupta family emails vouches for their authenticity.

So what exactly is radical economic transformation?

So what exactly is radical economic transformation?

Wits associate professor of economics Christopher Malikane speaks to Azania Mosaka about the term that is being bandied about.

‘My worst fear is being 80 years old and poor’ – famed actor Dr. John Kani

‘My worst fear is being 80 years old and poor’ – famed actor Dr. John Kani

"My earliest memory of money is my father saying, ‘Why do you want to do this thing? How are you going to feed the family?'"

Who is Advocate Tembeka Ngcukaitobi?

Who is Advocate Tembeka Ngcukaitobi?

The EFF lawyer stole the show during the state capture report court battle.

5 advantages of leasing instead of owning a car (lower monthly payments!)

5 advantages of leasing instead of owning a car (lower monthly payments!)

Want (or need) a new car? Dale Scorer (a wealth manager at AlphaWealth) reckons you should consider leasing.

3 easy questions could bag you R2000!

3 easy questions could bag you R2000!

WIN R2000! But only if you can prove you're a whiz of the MTN Biz Quiz by answering the following three questions...

Blesserfinder: Matching you with a sugar daddy near you

Blesserfinder: Matching you with a sugar daddy near you

Is social trend Blesserfinder, where girls are allegedly matching up with rich 'benefactors' in exchange for sex, a real thing?